The Cybersecurity Manufacturing Innovation Institute (CyManII) is an inclusive national research institute with major leading research universities in cybersecurity, smart and energy-efficient manufacturing, and deep expertise in research and development, supply chains, factory automation, and workforce development. 

Led by The University of Texas at San Antonio, CyManII leverages the strongest Department of Energy (DOE) national laboratories in the area, with Oak Ridge National Laboratory leading the nation in advanced manufacturing, Idaho National Laboratory leading in cybersecurity of industrial control systems and physical infrastructure, and Sandia National Laboratory is a national leader in supply chain management.